Gene Therapy Advances in Treating Neurodegenerative Disorders
Introduction Neurodegenerative disorders are among the most complex diseases of modern medicine. They are characterized by progressive loss in the …
mutation
Gene Therapy for Hemophilia: Progress, Challenges, and Future Directions
Introduction Hemophilia is an inherited disorder producing a deficiency of clotting factors, either factor VIII or factor IX, and has …
Genetic Counseling and Predictive Testing in Huntington’s Disease: Ethical Considerations and Impact
Introduction Huntington’s Disease (HD) is one of the most horrifying hereditary diseases that hits the central nervous system and causes …
Understanding Lynch Syndrome: Genetic and Molecular Insights
Introduction Lynch syndrome, or Hereditary Non-Polyposis Colorectal Cancer (HNPCC), is a frequent hereditary cancer predisposition with a strong relationship with …
The Role of Mitochondrial DNA in Neurodegenerative Diseases
Introduction Heterochromatin and its known role in energy production and management of the cells make it vital in the body, …
Advances in Understanding Chromosomal Abnormalities in Livestock
Introduction Chromosome aberrations in livestock have over the decades generated substantial attention and interest to be detected as owing enormous …
Genetic and Environmental Factors in Congenital Heart Disease (CHD)
Introduction Congenital heart disease (CHD) remains one of the major dilemmas in pediatric cardiology and genetics. CHD affects about 1% …
Exploring the Neurobiological Mechanisms of Fragile X Syndrome
Introduction FXS is the only known cause of intellectual disability, being primarily inherited as well as being one of the …
Advancements in Iron Chelation Therapy for Thalassemia Patients
Introduction Thalassemia is one of the blood disorders passed on to the offspring in which the human body fails to …
Innovations in DNA Cloning and Sequencing
Introduction DNA cloning and sequencing have been an overwhelming game-changing field in the past 50 years, establishing our knowledge of …