Atsushi Hirao - Genetic Mutations

Author Information

Atsushi Hirao is a prominent researcher affiliated with the Division of Molecular Genetics. His work extensively covers various aspects of genetics, with a strong focus on cellular and molecular mechanisms. His research aims to advance the understanding of genetic regulation and its implications in diseases such as cancer and hematopoietic disorders.

Research Contributions

Atsushi Hirao has made significant contributions to the field of genetics, particularly in understanding the cellular processes involved in immune function and cancer biology. Notable research includes the study of intracellular metabolic adaptation in T lymphocytes, the role of nutrients in hematopoietic stem cells, and the regulatory mechanisms of tumorigenicity in glioma stem cells. His work also explores the PI3K-Akt-mTORC1-S6K1/2 axis in Th17 differentiation and the implications of gut microbiota in hematopoietic homeostasis and leukemogenesis.

Aliases

Atsushi Hirao is also known by other aliases including A Hirao and A. Hirao, which are used interchangeably in various publications and academic settings.

Publication and Citation Metrics

Metric	Value
Citation Count	14,859
h-index	49
Paper Count	208

Publications:

Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes

DOI: 10.1016/j.isci.2022.104021

Year: 2022

The Role of Nutrients in Maintaining Hematopoietic Stem Cells and Healthy Hematopoiesis for Life

DOI: 10.3390/ijms23031574

Year: 2022

SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.

DOI: 10.1038/s42003-021-02950-0

Year: 2022

PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ.

DOI: 10.1016/j.celrep.2021.108886

Year: 2021

SMURF2 phosphorylation at Thr249 modifies the stemness and tumorigenicity of glioma stem cells by regulating TGF-β receptor stability

DOI: 10.1101/2021.04.27.441592

Year: 2021

Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway

DOI: 10.1038/s41419-021-03587-x

Year: 2021

[Role of the gut microbiota in hematopoietic homeostasis and leukemogenesis].

DOI: 10.11406/rinketsu.62.739

Year: 2021

Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner.

DOI: 10.1038/s41598-021-81076-z

Year: 2021

Mitochondrial fusion factor OPA1 sustains gefitinib-resistance in lung adenocarcinoma cells

DOI: 10.1254/JPSSUPPL.94.0_2-P2-LB50

Year: 2021

SMURF2 phosphorylation at Thr249 modifies the stemness and tumorigenicity of glioma stem cells by regulating TGF-β receptor stability

DOI: 10.21203/rs.3.rs-612377/v1

Year: 2021

What Are the Successes of Gene Therapy?

Is Genetic Counseling Recommended?

What is BLAST?

What Are the Future Directions in Studying Non-Coding Mutations?

What is Genome Editing?

What Causes Hemophilia?

Can Genetics Explain Individual Differences in Cognitive Abilities?

What are Non-Coding Regions?

How Does Genetic Counseling Assist During Pregnancy?

Are All Silent Mutations Neutral?

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