Annapoorni Rangarajan - Genetic Mutations

Author Information

Annapoorni Rangarajan is affiliated with the Department of Molecular Reproduction, Development and Genetics, and the Centre for BioSystems Science and Engineering at the Indian Institute of Science, Bangalore. Her research focuses on various aspects of cancer biology, specifically examining molecular mechanisms and pathways involved in cancer stem cells, drug resistance, and tumor microenvironments.

Research Contributions

Annapoorni Rangarajan has made significant contributions to the field of cancer research. Her work in 2022 includes studies on somatic mutations in gingivobuccal oral squamous cell carcinoma, the role of AMP-activated protein kinase (AMPK) in breast cancer stemness and drug resistance, and the development of a MEMS-based platform for rapid demarcation of tumors in breast biopsy tissues. In addition, Rangarajan's research delves into the expression of PD-1 and PD-L1 in Indian women with breast cancer and the role of prolactin-induced AMPK in stabilizing alveologenesis and lactogenesis through STAT5 signaling. Her earlier work in 2021 focused on the maintenance of AMPK activation and proline metabolism for the survival of matrix-deprived transformed cells, metabolic reprogramming for anoikis resistance in cancer, and the role of complementary and alternative medicine in wound healing.

Aliases

Annapoorni Rangarajan is also known by the aliases "A. Rangarajan" and "A Rangarajan."

Publication and Citation Metrics

Metric	Value
Citation Count	5336
h-index	34
Paper Count	102

Publications:

Somatic mutation analyses of stem-like cells in gingivobuccal oral squamous cell carcinoma reveals DNA damage response genes.

DOI: 10.1016/j.ygeno.2022.110308

Year: 2022

AMP- activated protein kinase (AMPK) promotes breast cancer stemness and drug resistance.

DOI: 10.1242/dmm.049203

Year: 2022

RapidET: a MEMS-based platform for label-free and rapid demarcation of tumors from normal breast biopsy tissues

DOI: 10.1038/s41378-021-00337-z

Year: 2022

PD-1 and PD-L1 Expression in Indian Women with Breast Cancer.

DOI: 10.4274/ejbh.galenos.2021.2021-5-2

Year: 2022

Prolactin-induced AMPK stabilizes alveologenesis and lactogenesis through regulation of STAT5 signaling

DOI: 10.1101/2022.02.15.480514

Year: 2022

Sustained AMPK Activation and Proline Metabolism Play Critical Roles in the Survival of Matrix-Deprived Transformed Cells

DOI: 10.3389/fcell.2021.771366

Year: 2021

Metabolic Reprogramming and the Control of Anoikis Resistance in Cancer

DOI: 10.1007/978-3-030-73856-3_2

Year: 2021

Challenges in Healing Wound: Role of Complementary and Alternative Medicine

DOI: 10.3389/fnut.2021.791899

Year: 2021

Correction to "Enhanced Metastatic Potential in a 3D Tissue Scaffold toward a Comprehensive in Vitro Model for Breast Cancer Metastasis".

DOI: 10.1021/acsami.1c14650

Year: 2021

Correction: Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor

DOI: 10.18632/oncoscience.546

Year: 2021

What Is the Mechanism Behind Asbestos-Induced Mutagenesis?

Is There a Cure for Autism Spectrum Disorder?

What Are the Ethical Considerations for CRISPR Technology?

How is Sickle Cell Trait Diagnosed?

What are DNA Molecules?

What Are the Side Effects of PARP Inhibitors?

What Causes the Genetic Mutation?

How Can Benzene-Induced Mutations Be Detected?

Are There Any Treatments Specifically Targeting BRCA1 and BRCA2 Mutations?

What Are the Challenges in Pharmacogenomics?

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