Charles M. Boone - Genetic Mutations

Author Information

Charles Boone is affiliated with the Donnelly Centre for Cellular and Biomolecular Research and the Department of Molecular Genetics at the University of Toronto, located at 160 College Street, Toronto, ON M5S 3E1, Canada. Additionally, he has an affiliation with the RIKEN Center for Sustainable Resource Science in Wako, Saitama, Japan.

Research Contributions

Charles Boone has made significant contributions to the field of genetics, focusing on a diverse range of topics including genetic background and mistranslation frequency, CRISPR screen reproducibility, the ubiquitin-proteasome system, chemical structural similarity, autophagy, and fungal-specific enzyme inhibitors. His research spans various applications of genetics and molecular biology, utilizing cutting-edge techniques such as machine learning, single-cell image analysis, and chemogenomic interactions. Recent publications include studies on mistranslating tRNASerUGG, reproducibility metrics for CRISPR screens, and the discovery of a fungal-selective glutaminyl tRNA synthetase inhibitor with potent activity against Candida albicans.

Aliases

Charles Boone is also known by the aliases Charles M Boone, Charles M. Boone, and Charlie Boone.

Publication and Citation Metrics

Metric Value
Citation Count 38,762
h-index 99
Paper Count 315

Publications:

DOI: 10.1101/2022.02.19.480892

Year: 2022

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