Eran Meshorer - Genetic Mutations

Author Information

Eran Meshorer is affiliated with the Department of Genetics and the Edmond and Lily Center for Brain Sciences (ELSC) at the Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel. His research primarily focuses on genetics, chromatin biology, stem cell biology, and neurogenetics.

Research Contributions

Eran Meshorer has made significant contributions to our understanding of chromatin dynamics, stem cell differentiation, and neurological diseases. Notable among his recent work is the development of "CloneSeq," a highly sensitive analysis platform for characterizing 3D-cultured single-cell-derived clones. His research also delves into the role of transposable elements as sensors of SARS-CoV-2 infection, the heterogeneity in transcriptional profiles in pluripotent stem cell-derived models of neurological diseases, and the regulation of parental imprinting using CRISPR/Cas9 screening in haploid human embryonic stem cells. Meshorer's work extends to mesoscale modeling, single-nucleosome tracking in stem cell differentiation, and the role of chromatin regulators like ZMYM2 in pluripotent stem cell growth and teratoma formation.

Aliases

Eran Meshorer has been published under various aliases, including "E Meshorer" and "E. Meshorer".

Publication and Citation Metrics

Metric	Value
Citation Count	9349
H-Index	42
Paper Count	177

Publications:

CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones.

DOI: 10.1016/j.devcel.2021.04.026

Year: 2021

Transposable elements as sensors of SARS-CoV-2 infection

DOI: 10.1101/2021.02.25.432821

Year: 2021

Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

DOI: 10.1186/s13059-021-02301-6

Year: 2021

Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells

DOI: 10.1038/s41467-021-26949-7

Year: 2021

Mesoscale Modeling and Single-Nucleosome Tracking Reveal Remodeling of Clutch Folding and Dynamics in Stem Cell Differentiation

DOI: 10.1016/j.celrep.2020.108614

Year: 2021

The upstream 5′ splice site remains associated to the transcription machinery during intron synthesis

DOI: 10.1038/s41467-021-24774-6

Year: 2021

Impaired activation of Transposable Elements in SARS-CoV-2 infection

DOI: 10.1101/2021.02.25.432821

Year: 2021

The Chromatin Regulator ZMYM2 Restricts Human Pluripotent Stem Cell Growth and Is Essential for Teratoma Formation

DOI: 10.1016/j.stemcr.2020.05.014

Year: 2020

Histone H1 eviction by the histone chaperone SET reduces cell survival following DNA damage.

DOI: 10.1242/jcs.235473

Year: 2020

Differential DNA methylation of vocal and facial anatomy genes in modern humans

DOI: 10.1038/s41467-020-15020-6

Year: 2020

How Do Missense Mutations Differ from Other Types of Mutations?

How Can We Protect Ourselves from Chemical Mutagens?

How Does it Differ from Autosomal Dominant Inheritance?

What Are the Common PARP Inhibitors?

What Ethical Considerations Arise From Genetic Research?

How Do Neutral Mutations Occur?

How Does Sequencing Help in Identifying Mutations?

How does Radiation Cause Induced Mutations?

What are the Limitations and Challenges?

What Genetic Conditions Are Commonly Addressed in Occupational Therapy?

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