Marju Orho–melander - Genetic Mutations

Author Information

Marju Orho-Melander is a prominent researcher affiliated with the Department of Clinical Sciences in Malmö at Lund University, Sweden. Her work extends to the Program in Medical and Population Genetics at The Broad Institute in Cambridge, MA. Marju Orho-Melander's research focuses on genetic and metabolic aspects of diseases, particularly those related to cardiovascular health and diabetes.

Research Contributions

Marju Orho-Melander has made significant contributions to the understanding of genetic and metabolic factors influencing health outcomes, particularly in the context of cardiovascular disease and diabetes. Her recent work involves exploring the associations between gene expressions, metabolic signatures, and disease risk, such as the role of osteomodulin gene expression in plaque stability and cardiovascular events, as well as the impact of metabolomic profiles on obesity and diabetes. Her research also investigates the influence of dietary factors and gut microbiome composition on metabolic health.

Aliases

Throughout her career, Marju Orho-Melander has been referenced under several aliases, including Marju Orho–melander, M. Orho-melander, and variations thereof. These aliases represent different stylings of her name used in academic publications.

Publication and Citation Metrics

Metric	Value
Citation Count	39,528
H-Index	82
Paper Count	411

Publications:

Osteomodulin Gene Expression Is Associated With Plaque Calcification, Stability, and Fewer Cardiovascular Events in the CPIP Cohort

DOI: 10.1161/STROKEAHA.121.037223

Year: 2022

Metabolome-Defined Obesity and the Risk of Future Type 2 Diabetes and Mortality.

DOI: 10.2337/dc21-2402

Year: 2022

A healthy dietary metabolic signature is associated with a lower risk for type 2 diabetes and coronary artery disease

DOI: 10.1186/s12916-022-02326-z

Year: 2022

The inverse association between a fish consumption biomarker with gingival inflammation and periodontitis - a population-based study.

DOI: 10.1111/jcpe.13602

Year: 2022

Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques.

DOI: 10.1093/eurheartj/ehab920

Year: 2022

Proteomic Profiles of Body Mass Index and Waist-to-Hip Ratio and their Role in Incidence of Diabetes.

DOI: 10.1210/clinem/dgac140

Year: 2022

Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol

DOI: 10.2337/figshare.16826305.v1

Year: 2021

Hyperglycaemia-associated Caspase-3 predicts diabetes and coronary artery disease events

DOI: 10.1111/joim.13327

Year: 2021

An online atlas of human plasma metabolite signatures of gut microbiome composition

DOI: 10.1101/2021.12.23.21268179

Year: 2021

Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction

DOI: 10.1038/s41467-021-25014-7

Year: 2021

How Does Substitution Occur?

Can Neurodevelopmental Disorders Be Prevented?

What Are Mutations?

What Are the Implications for Treatment and Management?

Why is Hemoglobin Electrophoresis Important?

What Are the Common Genetic Disorders Linked to Infertility?

How Does Asbestos Lead to Genetic Mutations?

How Do Chemicals Cause Genetic Mutations?

How Does NGS Work?

What is CRISPR-Cas9?

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