Serge Nef And Patrick Nef - Genetic Mutations

Author Information

Serge Nef is affiliated with the Department of Genetic Medicine and Development, University of Geneva, and the iGE3, Institute of Genetics and Genomics of Geneva, University of Geneva, located in Geneva, Switzerland. His work primarily involves the study of genetic influences on reproductive health and development.

Research Contributions

Serge Nef has made substantial contributions to the fields of genetics and reproductive biology. His research includes investigations into the oligogenic heterozygous inheritance of sperm abnormalities, the impact of specific gene loss on sexual differentiation in mice, and the identification of potential cells of origin for MYC rhabdoid tumors through single-cell transcriptomics. His work also explores the effects of maternal occupational exposure to endocrine-disrupting chemicals on semen parameters in adulthood and the regulation of steroidogenesis in fetal and adult mouse Leydig cells. His studies are pivotal in understanding genetic and environmental factors that influence reproductive health.

Aliases

S Nef, S. Nef, Serge Nef, Serge Nef And Patrick Nef

Publication and Citation Metrics

Citation Count	10,149
H-index	53
Paper Count	166

Publications:

Oligogenic heterozygous inheritance of sperm abnormalities in mouse.

DOI: 10.7554/eLife.75373

Year: 2022

Loss of NEDD4 causes complete XY gonadal sex reversal in mice

DOI: 10.1038/s41419-022-04519-z

Year: 2022

Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors

DOI: 10.1038/s41467-022-29152-4

Year: 2022

Maternal occupational exposure to endocrine-disrupting chemicals during pregnancy and semen parameters in adulthood: results of a nationwide cross-sectional study among Swiss conscripts.

DOI: 10.1093/humrep/deab034

Year: 2021

Maternal occupational exposure to endocrine-disrupting chemicals during pregnancy and semen parameters in adulthood: results of a nationwide cross-sectional study among Swiss conscripts

DOI: 10.1530/ey.18.15.10

Year: 2021

Oligogenic heterozygous inheritance of sperm abnormalities in mouse

DOI: 10.1101/2021.11.15.468601

Year: 2021

Specific transcriptomic signatures and dual regulation of steroidogenesis between fetal and adult mouse Leydig cells

DOI: 10.1101/2021.04.14.439819

Year: 2021

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

DOI: 10.1101/2021.09.15.460431

Year: 2021

The antidepressant Sertraline inhibits CatSper Ca2+ channels in human sperm

DOI: 10.1093/humrep/deab190

Year: 2021

TRIM28-dependent SUMOylation protects the adult ovary from the male pathway

DOI: 10.1101/2021.03.24.436749

Year: 2021

What is Mutation?

What Are the Potential Consequences of Radiation-Induced Mutations?

What Are Developmental Disorders?

What are the sources of PAH exposure?

What Types of Mutations Occur in the CFTR Gene?

Can Genetic Testing Help in Identifying Asbestos-Related Risks?

What is Epigenetics?

What is Sanger Sequencing?

How Do Mutations in Non-Coding Regions Affect Gene Expression?

What Are Some Examples of Gene Amplification in Disease?

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