Shogo Ozawa - Genetic Mutations

Author Information

Shogo Ozawa is affiliated with the Department of Pharmacodynamics and Molecular Genetics at the School of Pharmacy, Iwate Medical University, located in Iwate, Japan. His work primarily involves research in the fields of pharmacodynamics and molecular genetics, contributing to understanding complex biological and chemical interactions.

Research Contributions

Shogo Ozawa has made significant contributions to the fields of pharmacogenomics, toxicology, and cancer research. His recent work involves understanding the role of the aryl hydrocarbon receptor in DNA methylation and stress response pathways, as well as exploring cellular resistance mechanisms in colorectal cancer. He has also investigated the kinetics of pesticide toxicity and drug-induced liver injury, showcasing a broad interest in both environmental and clinical pharmacology.

Aliases

Shogo Ozawa is also known by the aliases S Ozawa and S. Ozawa. These variations may appear in different publications and databases.

Publication and Citation Metrics

Metric	Value
Total Citations	7,062
H-index	50
Total Papers	211

Publications:

Aryl hydrocarbon receptor as a DNA methylation reader in the stress response pathway.

DOI: 10.1016/j.tox.2022.153154

Year: 2022

β-naphthoflavone-induced upregulation of CYP1B1 expression is mediated by the preferential binding of aryl hydrocarbon receptor to unmethylated xenobiotic responsive elements

DOI: 10.3892/etm.2021.10846

Year: 2021

Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review

DOI: 10.20517/cdr.2021.82

Year: 2021

Case analysis of kinetics investigations in toxicity studies of pesticides to identify the nonlinearity of internal exposure and the influences of nonlinearity on the toxicological interpretation of pesticide residue.

DOI: 10.1016/j.yrtph.2021.104958

Year: 2021

Pharmacogenomics and Personalized Medicine

DOI: 10.3390/books978-3-03936-731-3

Year: 2020

Recent Progress in Prediction Systems for Drug-induced Liver Injury Using in vitro Cell Culture.

DOI: 10.2174/1872312814666201202112610

Year: 2020

Aryl Hydrocarbon Receptor Mediates Cell Proliferation Enhanced by Benzo[a]pyrene in Human Lung Cancer 3D Spheroids

DOI: 10.1080/07357907.2019.1655760

Year: 2019

[Drug-Drug Interactions with Consideration of Pharmacogenetics].

DOI: 10.1248/yakushi.17-00191-5

Year: 2018

Differential sensitization of two human colon cancer cell lines to the antitumor effects of irinotecan combined with 5-aza-2'-deoxycytidine.

DOI: 10.3892/ol.2018.7883

Year: 2018

The regulation mechanism of AhR activated by benzo[a]pyrene for CYP expression are different between 2D and 3D culture of human lung cancer cells.

DOI: 10.1016/j.dmpk.2018.04.002

Year: 2018

How Does Sequencing Help in Identifying Mutations?

What is Mutagenesis?

How do Environmental Factors Influence Genetic Mutations?

What is the Role of Neutral Mutations in Evolution?

What is the Role of Epigenetics in Mutations?

What are Zinc Finger Nucleases (ZFNs)?

How Can Benzene-Induced Mutations Be Detected?

How Effective Are PARP Inhibitors?

What Treatments are Available for CFTR-Related Conditions?

What Are the Implications for Treatment and Management?

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