Andrew Bruce Single - Genetic Mutations

Author Information

Andrew Bruce Single is affiliated with the Cancer Genetics Laboratory, Centre for Translational Cancer Research (Te Aho Matatū), Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand. His research primarily focuses on cancer genetics and translational cancer research, aiming to bridge the gap between laboratory findings and clinical applications.

Research Contributions

Andrew Bruce Single has made significant contributions in the fields of cancer genetics, chemotherapy resistance, lung inflammation, fibrosis, and the development of therapeutic strategies targeting E-cadherin-deficient cancers. His work on the regulation of extracellular matrix-cell communication by chemotherapy has implications for therapy resistance. Additionally, he has explored the role of OGG1 inhibition in attenuating pulmonary inflammation and lung fibrosis, and has investigated the effects of citrullination on extracellular histone H3.1. His research also includes high-throughput screening for synthetic lethal compounds and the development of animal models for chronic obstructive pulmonary disease (COPD) and related respiratory disorders.

Aliases

Andrew Bruce Single is known by several aliases, including A. B. Single, Andrew B. Single, Andrew B. Single, Andrew Bruce Single, A. Single, and Andrew Single.

Publication and Citation Metrics

Metric Value
Total Papers 16
Total Citations 231
H-index 8

Publications:

DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6532

Year: 2020

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