Why is Third Generation Sequencing Important for Genetic Mutations?
The ability of TGS to produce longer reads is crucial for identifying and understanding genetic mutations. Long reads can span entire genes or regulatory regions, making it easier to detect structural variants such as insertions, deletions, and inversions that shorter reads from NGS might miss. This is particularly important for uncovering mutations in regions of the genome that are difficult to sequence with traditional methods, such as repetitive sequences or areas with high GC content.
