Bart Deplancke - Genetic Mutations

Author Information

Bart Deplancke is a prominent researcher affiliated with the Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL) in Lausanne, Switzerland. He is also associated with the Swiss Institute of Bioinformatics, located in Lausanne, Switzerland. His work is focused on various aspects of genetics and systems biology.

Research Contributions

Bart Deplancke has made significant contributions to the field of genetics, particularly in spatial proteogenomics, neuro-toxicogenomics, and single-cell transcriptomics. His recent publications include studies on hepatic macrophage niches, TMT-induced neurotoxicity, germline variants in leukemia, and the Fly Cell Atlas. His work often employs advanced techniques such as single-nucleus transcriptomics and deterministic scRNA-seq to explore the intricate details of cellular and molecular biology.

Aliases

B Deplancke, Bart Deplancke

Publication and Citation Metrics

Metric	Value
Total Citation Count	13,155
H-Index	57
Total Paper Count	194

Publications:

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

DOI: 10.1016/j.cell.2021.12.018

Year: 2022

Neuro-toxicogenomic mapping of TMT induced neurotoxicity using human minibrain reveals associated adverse outcome events

DOI: 10.1101/2022.01.21.477206

Year: 2022

A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation.

DOI: 10.1038/s41467-022-29625-6

Year: 2022

Shared acute phase traits in effector and memory human CD8 T cells

DOI: 10.1016/j.crimmu.2021.12.002

Year: 2022

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

DOI: 10.1126/science.abk2432

Year: 2022

Deterministic scRNA-seq captures variation in intestinal crypt and organoid composition.

DOI: 10.1038/s41592-021-01391-1

Year: 2022

Author response: The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression

DOI: 10.7554/ELIFE.63726.SA2

Year: 2021

Spatial proteogenomics reveals distinct and evolutionarily-conserved hepatic macrophage niches

DOI: 10.1101/2021.10.15.464432

Year: 2021

Postnatal lymph node expansion of stromal progenitors towards reticular and CD34+ stromal cell subsets is determined by distinct transcriptional programs

DOI: 10.21203/rs.3.rs-596484/v1

Year: 2021

Recent advances in trajectory inference from single-cell omics data

DOI: 10.1016/J.COISB.2021.05.005

Year: 2021

How are Autosomal Recessive Disorders Diagnosed?

What is Genome Editing?

What Types of Mutations Are Commonly Observed?

How are Results Validated?

What are Synonymous Codons?

What Are Some Examples of Pharmacogenomic Applications?

How Effective Are PARP Inhibitors?

What are Some Examples of Medications Affected by Genetic Mutations?

What is Sickle Cell Trait?

What Are the Different Types of Mutations?

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