What Are the Limitations of Third Generation Sequencing?
Despite its advantages, TGS also has some limitations: 1. Accuracy: While TGS can detect long sequences, the error rates can be higher compared to NGS. However, advances in error-correction algorithms are continually improving accuracy. 2. Cost: TGS technologies are often more expensive than traditional sequencing methods, though costs are decreasing as the technology matures. 3. Data Handling: The large volume of data generated by TGS requires significant computational resources for storage and analysis.
