Igor V. Sharakhov - Genetic Mutations

Author Information

Igor V. Sharakhov is a researcher affiliated with the Laboratory of Ecology, Genetics and Environmental Protection at Tomsk State University in Tomsk, Russia. His work primarily focuses on genetics, with notable research on chromatin architecture and its role in gene expression and genome organization, particularly in Drosophila and Anopheles mosquitoes.

Research Contributions

Igor V. Sharakhov has made significant contributions to the field of genetics, particularly in understanding the 3D genome organization and chromatin architecture. His research in 2022 includes studies on the impact of chromatin's proximity to the nuclear envelope on gene expression, the structural folding patterns of chromatin, and the stabilization of chromatin architecture by interactions with the nuclear envelope. Additionally, his work on Anopheles mosquitoes has unveiled new principles of genome organization in insects, which could have implications for understanding malaria vector biology.

Aliases

Igor V. Sharakhov has published under various aliases, including I. V. Sharakhov, I V Sharakhov, Igor V Sharakhov, and Igor Sharakhov. These variations are used interchangeably in academic publications.

Publication and Citation Metrics

Metric	Value
Citation Count	4270
h-index	29
Paper Count	175

Publications:

Proximity of chromatin to the nuclear envelope, does not, by itself, affect gene expression in drosophila

DOI: 10.1016/j.bpj.2021.11.1929

Year: 2022

Extracting structural folding pattern of chromatin using chromatin condensation data using HiCNN[12] or HiCNN2[13] approaches Metrics for evaluation: Comparing the result’s mean squared error and Pearson’s correlation coefficients with experimental high-resolution Hi-C data

DOI:

Year: 2022

Strong interactions between highly-dynamic lamina-associated domains and the nuclear envelope stabilize the 3D architecture of Drosophila interphase chromatin

DOI: 10.1101/2022.01.28.478236

Year: 2022

The probability of chromatin to be at the nuclear lamina has no systematic effect on its transcription level

DOI: 10.1101/2022.02.17.480932

Year: 2022

3D architecture of Drosophila interphase chromatin is stabilized by relatively strong attractive interactions between highly-dynamic lamina-associated domains and nuclear envelope

DOI: 10.1016/j.bpj.2021.11.936

Year: 2022

Anopheles mosquitoes reveal new principles of 3D genome organization in insects.

DOI: 10.1038/s41467-022-29599-5

Year: 2022

Single-cell Hi-C: how modeling can augment experiment?

DOI: 10.1016/j.bpj.2021.11.939

Year: 2022

Physical Mapping of the Anopheles (Nyssorhynchus) darlingi Genomic Scaffolds

DOI: 10.3390/insects12020164

Year: 2021

Chromosome-level genome assemblies of the malaria vectors Anopheles coluzzii and Anopheles arabiensis

DOI: 10.1093/gigascience/giab017

Year: 2021

Asymmetric Phenotypes of Sterile Hybrid Males From Reciprocal Crosses Between Species of the Anopheles gambiae Complex

DOI: 10.3389/fevo.2021.660207

Year: 2021

How is the Delta F508 Mutation Diagnosed?

What Types of Prenatal Tests Are Available?

What is Hemoglobin S (HbS)?

Is There a Cure for Autism Spectrum Disorder?

How is Sickle Cell Disease Inherited?

What are the Challenges Ahead?

How are Mutations Detected?

What are the Options for Individuals with BRCA1 or BRCA2 Mutations?

Is All Evolution Neutral?

What Are the Symptoms of Hemophilia?

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