Margarita Zachariou - Genetic Mutations

Author Information

Margarita Zachariou is affiliated with the Medical School at the University of Nicosia and the Bioinformatics Department at the Cyprus Institute of Neurology and Genetics, located in Nicosia, Cyprus. Her research is primarily focused on the intersection of genetics and bioinformatics, contributing significantly to the understanding of complex biological networks and disease mechanisms.

Research Contributions

Margarita Zachariou has made substantial contributions to the fields of genetics and bioinformatics, with a particular focus on network-based analyses and multi-omics data integration. Her recent work includes investigating stage-specific drug repurposing for Alzheimer's disease, identifying novel osteoarthritis-associated genes, and exploring virulence measures in SARS-CoV-2 strains through generalized linear models. She has also contributed to research on antimicrobial peptides within bacterial proteomes and has been involved in multiplex drug repurposing approaches for COVID-19. Additionally, her work addresses age-related expression patterns in skeletal muscles.

Aliases

Margarita Zachariou has published under the names "M. Zachariou" and "Margarita Zachariou."

Publication and Citation Metrics

Metric	Value
Citation Count	409
h-index	13
Paper Count	43

Publications:

Network-based stage-specific drug repurposing for Alzheimer’s disease

DOI: 10.1016/j.csbj.2022.03.013

Year: 2022

A SYSTEMATIC META-ANALYSIS AND MULTI-SOURCE INFORMATION NETWORK IDENTIFY NOVEL OSTEOARTHRITIS-ASSOCIATED GENES

DOI: 10.1016/j.joca.2022.02.147

Year: 2022

Identifying Novel Osteoarthritis-Associated Genes in Human Cartilage Using a Systematic Meta-Analysis and a Multi-Source Integrated Network

DOI: 10.3390/ijms23084395

Year: 2022

Generalized linear models provide a measure of virulence for specific mutations in SARS-CoV-2 strains

DOI: 10.1371/journal.pone.0238665

Year: 2021

Empirically constrained network models for contrast-dependent modulation of gamma rhythm in V1

DOI: 10.1016/j.neuroimage.2021.117748

Year: 2021

Putative Antimicrobial Peptides Within Bacterial Proteomes Affect Bacterial Predominance: A Network Analysis Perspective

DOI: 10.3389/fmicb.2021.752674

Year: 2021

Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19

DOI: 10.1093/bib/bbab114

Year: 2021

Age-Related Exosomal and Endogenous Expression Patterns of miR-1, miR-133a, miR-133b, and miR-206 in Skeletal Muscles

DOI: 10.3389/fphys.2021.708278

Year: 2021

Breaking barriers for women in science

DOI:

Year: 2020

PathWalks: identifying pathway communities using a disease-related map of integrated information

DOI: 10.1093/bioinformatics/btaa291

Year: 2020

How Does NGS Work?

Do Genetic Mutations Always Have Positive Effects?

What is the Role of Epigenetics in Brain Development?

How Do Genetic Mutations Cause Developmental Disorders?

What is the Delta F508 Mutation?

How Are Genetic Mutations Mapped in Phylogenetic Trees?

Is There Any Treatment or Management Required?

What Are the Common Types of Errors?

What are Mutagens?

What Causes the Mutation in HbS?

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