Can Mutations in Non-Coding Regions Cause Diseases?
Yes, mutations in non-coding regions can lead to various diseases. For instance: - Cancer: Mutations in enhancers and promoters can lead to the overexpression of oncogenes or the underexpression of tumor suppressor genes. - Genetic disorders: Mutations in non-coding RNAs can lead to diseases such as Fragile X syndrome and certain types of muscular dystrophy. - Complex diseases: Variations in non-coding regions have been associated with diseases like diabetes, heart disease, and neurological disorders.
