Peter J. Donnelly - Genetic Mutations

Author Information

Peter J. Donnelly is a distinguished researcher affiliated with The Wellcome Trust Centre for Human Genetics and the Department of Statistics at the University of Oxford. His work primarily focuses on genetics and the statistical methods that underpin genetic research. With his affiliation in a leading institution, Peter J. Donnelly contributes significantly to the understanding of human genetics and its implications on health.

Research Contributions

Peter J. Donnelly's research contributions are extensive and influential in the field of genetics. His work spans various topics including the development of risk prediction tools for cardiovascular diseases, the exploration of polygenic risk scores, and the study of recombination processes in meiosis. Notably, his research has enhanced the prediction of coronary artery disease and explored the genetic basis of fertility and evolutionary biology through studies on species such as the platypus and echidna. His innovative work on integrating clinical and polygenic data has paved the way for more accurate disease prediction models.

Aliases

Throughout his academic career, Peter J. Donnelly has been referenced under several aliases including Peter Donnelly, P. J. Donnelly, P Donnelly, and P. Donnelly. These variations often appear in publications and citations, reflecting common practices in academic authorship.

Publication and Citation Metrics

Metric	Value
Total Papers	248
Total Citations	88,741
H-index	93

Publications:

Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries.

DOI: 10.1016/j.amjcard.2021.02.032

Year: 2021

Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary

DOI: 10.1093/molbev/msab269

Year: 2021

Abstract 11316: Analytical Validation for an Integrated Risk Tool for Cardiovascular Disease Combining Conventional Risk Factors and Polygenic Risk Inferred from Snp Array and Low-Pass Whole Genome Sequencing

DOI: 10.1161/circ.144.suppl_1.11316

Year: 2021

Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction

DOI: 10.1161/CIRCGEN.120.003304

Year: 2021

Platypus and echidna genomes reveal mammalian biology and evolution

DOI: 10.1038/s41586-020-03039-0

Year: 2021

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates

DOI: 10.1016/j.molcel.2020.06.015

Year: 2020

Complement genes contribute sex-biased vulnerability in diverse illnesses

DOI: 10.1038/s41586-020-2277-x

Year: 2020

Author response: ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair

DOI: 10.7554/elife.53392.sa2

Year: 2020

An integrated polygenic and clinical risk tool enhances coronary artery disease prediction

DOI: 10.1101/2020.06.01.20119297

Year: 2020

ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair

DOI: 10.7554/eLife.53392

Year: 2020

What are the Global Implications?

What is the Role of Precision Medicine in This Context?

How do Genetic Mutations Influence Cancer?

Are there any limitations to ZFNs?

Are There Any Treatments Specifically Targeting BRCA1 and BRCA2 Mutations?

How Do Chemicals Cause Genetic Mutations?

How Do Missense Mutations Occur?

What are DNA Molecules?

How are Patients Monitored During TKI Therapy?

What are Current Research Trends in Genetic Mutations?

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