Author Information
Pavel Janscak is a distinguished scientist affiliated with the Institute of Molecular Cancer Research at the University of Zurich, located in Zurich, Switzerland. His research is primarily focused on the molecular mechanisms underlying DNA replication, transcription, and genome stability, with a particular interest in the role of helicases and other proteins in maintaining genomic integrity.Research Contributions
Pavel Janscak has made significant contributions to the understanding of DNA replication and repair mechanisms. His research has highlighted the critical roles of various proteins, such as RECQ5 helicase and RAD51, in processing stalled replication forks and managing co-transcriptional R-loops, which are crucial for maintaining genome stability. His work on the MutSβ complex and its regulation of telomeric R-loops in ALT cancer cells has provided insights into telomere integrity and cancer biology. Furthermore, his studies on the ALPK1/TIFA/NF-κB axis have linked bacterial carcinogens to replication stress, offering potential therapeutic targets for cancer treatment.Aliases
Pavel Janscak is known by several aliases in the scientific community, including P Janscák, P Janscak, P. Janščák, and P. Janscak. These variations are commonly found in different publications and databases.Publication and Citation Metrics
| Metric |
Value |
| Total Citations |
4159 |
| h-index |
38 |
| Total Papers |
79 |
