Philippe Pasero - Genetic Mutations

Author Information

Philippe Pasero is associated with the Institute of Human Genetics, CNRS UMR9002 and University of Montpellier in France. His work is recognized under the Equipe Labéllisée Ligue Contre le Cancer. Philippe Pasero's research is primarily rooted in the field of genetics, with a focus on understanding the complexities of DNA replication and transcription mechanisms.

Research Contributions

Philippe Pasero has made significant contributions to the understanding of transcription-driven conflicts and replication stress. His research has explored the roles of transcription-replication conflicts in therapeutic interventions, as seen in multiple myeloma, and the targeting of cellular iron homeostasis in diffuse large B cell lymphoma. His recent works delve into the intricacies of DNA damage response, RNA:DNA hybrid structures, and their implications in genomic stability and cancer therapy. Through his extensive research, Philippe Pasero has provided valuable insights into the mechanisms of DNA replication and their broader impact on cellular function and disease.

Aliases

Philippe Pasero is also known by several aliases including P Pasero and P. Pasero.

Publication and Citation Metrics

Metric	Value
Citation Count	8130
H-index	52
Paper Count	170

Publications:

Sen1 is a master regulator of transcription-driven conflicts

DOI: 10.1101/2022.02.09.479708

Year: 2022

Top1p targeting by Fob1p at the ribosomal Replication Fork Barrier does not account for camptothecin sensitivity in Saccharomyces cerevisiae cells

DOI: 10.17912/micropub.biology.000514

Year: 2022

Targeting cellular iron homeostasis with ironomycin in diffuse large B cell lymphoma.

DOI: 10.1158/0008-5472.CAN-21-0218

Year: 2022

Toxic R-loops: Cause or consequence of replication stress?

DOI: 10.1016/j.dnarep.2021.103199

Year: 2021

IRONOMYCIN KILLS DIFFUSE LARGE B‐CELL LYMPHOMA CELLS BY TARGETING CELLULAR IRON HOMEOSTASIS

DOI: 10.1002/hon.79_2881

Year: 2021

Exploiting Transcription-Replication Conflicts As a Novel Therapeutic Intervention in Multiple Myeloma

DOI: 10.1182/blood-2021-151530

Year: 2021

Replication stress: from chromatin to immunity and beyond.

DOI: 10.1016/j.gde.2021.08.004

Year: 2021

Targeting the DNA damage response in immuno-oncology: developments and opportunities.

DOI: 10.1038/s41568-021-00386-6

Year: 2021

Decision letter: The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replisome collisions

DOI: 10.7554/elife.72286.sa1

Year: 2021

RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators

DOI: 10.1038/s41375-021-01234-0

Year: 2021

What is Gene Therapy?

How Do Genetic Mutations Cause Cystic Fibrosis?

What are the Effects of CNVs?

How Does NGS Work?

How is Biotechnology Applied in Medicine?

How is Genetic Testing Used in Diagnosis?

What are Immunotherapies?

What is CRISPR-Cas9?

What Are the Causes of Transversions?

How Do We Address Inequality in Access to Genetic Treatments?

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