Takashi Fujita - Genetic Mutations

Author Information

Takashi Fujita is a prominent researcher affiliated with the Laboratory of Molecular Genetics at the Institute for Frontier Life and Medical Science, Kyoto University, Kyoto, Japan. His extensive work in the field of genetics, particularly in antiviral research and molecular mechanisms, has made significant contributions to understanding viral infections and immune responses.

Research Contributions

Takashi Fujita has made substantial contributions to the field of genetics and virology through his research on antiviral substances, virus-induced cell death, and the immune response to viral infections. His recent work includes the development of antiviral lignin from sugarcane bagasse and beech wood, the role of RNA helicase DDX3 in IFNB transcription, and the mechanisms by which HBV evades apoptosis. His research on Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and its non-structural proteins has provided insights into cytokine storms and viral pathogenesis. Additionally, his studies on psoriasis-like skin disorders and type I interferon signaling in CD8+ T cells highlight his broad impact on understanding immune responses and viral interactions at the molecular level.

Aliases

Takashi Fujita is also known by the aliases T Fujita and T. Fujita.

Publication and Citation Metrics

Metric	Value
Citation Count	41,376
H-index	84
Paper Count	269

Publications:

Adsorptive Inhibition of Enveloped Viruses and Nonenveloped Cardioviruses by Antiviral Lignin Produced from Sugarcane Bagasse via Microwave Glycerolysis.

DOI: 10.1021/acs.biomac.1c01209

Year: 2022

The RNA helicase DDX3 promotes IFNB transcription via enhancing IRF-3/p300 holocomplex binding to the IFNB promoter

DOI: 10.1038/s41598-022-07876-z

Year: 2022

HBV upregulates TRAIL-R3 expression in hepatocytes for escaping both cell apoptosis and suppression of their replication by TRAIL.

DOI: 10.1093/infdis/jiac044

Year: 2022

Virus-infection in cochlear supporting cells induces audiosensory receptor hair cell death by TRAIL-induced necroptosis

DOI: 10.1371/journal.pone.0260443

Year: 2021

The Role of Non-Structural Protein NSs in the Pathogenesis of Severe Fever with Thrombocytopenia Syndrome

DOI: 10.3390/v13050876

Year: 2021

Conversion of Beech Wood into Antiviral Lignin–Carbohydrate Complexes by Microwave Acidolysis

DOI: 10.1021/ACSSUSCHEMENG.1C01450

Year: 2021

Restoration of type I interferon signaling in intrahepatically primed CD8+ T cells promotes functional differentiation

DOI: 10.1172/jci.insight.145761

Year: 2021

Production of antiviral substance from sugarcane bagasse by chemical alteration of its native lignin structure through microwave solvolysis.

DOI: 10.1002/cssc.202000490

Year: 2020

Psoriasis-like skin disorder in transgenic mice expressing a RIG-I Singleton-Merten syndrome variant.

DOI: 10.1093/intimm/dxaa071

Year: 2020

The Nonstructural Protein NSs of Severe Fever with Thrombocytopenia Syndrome Virus Causes a Cytokine Storm through the Hyperactivation of NF-κB

DOI: 10.1128/MCB.00542-20

Year: 2020

What Are the Benefits of Pharmacogenomics?

How Does Sequencing Help in Identifying Mutations?

Are There Any Risks Associated with Beneficial Mutations?

How Do Genes Work?

What Are the Future Directions in Sickle Cell Disease Research?

What are Immunotherapies?

Are There Examples of Genetic Mutations Providing Resistance to Infectious Diseases?

What are Point Mutations?

How Do Genetic Mutations Affect Fertility?

What Are the Limitations of CGH?

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