The consequences of transversions can range from benign to severe, depending on where in the gene they occur and the functional importance of the affected amino acid. For instance, a transversion in a critical region of a gene may lead to a nonfunctional protein, potentially resulting in genetic disorders or diseases such as cancer. Conversely, some transversions may have little to no impact on the organism, particularly if they occur in non-coding regions or lead to silent mutations.