asbestos

What Is the Mechanism Behind Asbestos-Induced Mutagenesis?

The mechanism of asbestos-induced mutagenesis involves several pathways. Chronic inflammation caused by asbestos fibers leads to the production of ROS and nitrogen species, which directly damage DNA. Additionally, asbestos can interfere with the mitotic spindle during cell division, causing chromosomal abnormalities and aneuploidy.

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How Does Sanger Sequencing Compare to Next-Generation Sequencing (NGS)?
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