Several genes have been linked to an increased risk of heart disease. Some of the most studied genes include:
LDLR - Mutations in this gene can cause familial hypercholesterolemia. MYH7 - Mutations can lead to hypertrophic cardiomyopathy, a condition characterized by thickened heart muscle. SCN5A - Mutations can cause arrhythmias, such as Brugada syndrome. APOB - Mutations can result in elevated cholesterol levels and increased heart disease risk. PCSK9 - Certain mutations can lower cholesterol levels and reduce heart disease risk, while others can have the opposite effect.
