Kevan m. Shokat - Genetic Mutations

Author Information

Kevan M. Shokat is a renowned researcher affiliated with the Department of Cellular and Molecular Pharmacology at the University of California, San Francisco. He is also associated with the Howard Hughes Medical Institute at the same university. His research primarily focuses on cellular and molecular pharmacology, with significant contributions to understanding and targeting challenging biological molecules in disease contexts.

Research Contributions

Kevan M. Shokat has made substantial contributions to the field of pharmacology, particularly in the development of innovative strategies to target previously 'undruggable' molecules like KRAS and mTOR. His recent work includes exploring vulnerabilities in KRAS for therapeutic engagement, investigating drug resistance mechanisms in prostate cancer, and developing tissue-specific mTOR inhibitors to minimize side effects. Additionally, his research extends to understanding immune evasion by SARS-CoV-2 and the oncogenic potential of gene fusions. His efforts in drug discovery and development have had a significant impact on cancer biology and treatment strategies.

Aliases

Kevan M. Shokat is known by several aliases, including K M Shokat, Kevan M Shokat, Kevan M. Shokat, K. M. Shokat, K. Shokat, Kevanm. Shokat, and Kevan Shokat. These variations may appear in different publications and databases.

Publication and Citation Metrics

Metric Value
Total Citation Count 58,664
H-index 128
Total Paper Count 647

Publications:

DOI: 10.1038/s41589-022-00985-w

Year: 2022

DOI: 10.1021/acs.jmedchem.2c00099

Year: 2022

DOI: 10.1038/s41586-022-04653-w

Year: 2022

DOI: 10.1158/1535-7163.MCT-21-0820

Year: 2022

DOI: 10.1242/dmm.049468

Year: 2022

DOI: 10.1101/2022.03.08.483534

Year: 2022

DOI:

Year: 2022

DOI: 10.1038/s41388-022-02179-z

Year: 2022

DOI: 10.1038/s41467-021-24567-x

Year: 2021

DOI: 10.1146/annurev-cancerbio-041621-012549

Year: 2021

Frequently asked queries:
How do Genetic Mutations Affect Health?
What Is the Role of Genetics in Cognitive Development?
How is Gene Amplification Detected?
What are some examples of inherited genetic disorders?
How do Viral Vectors Work?
How are Synonymous Codons Studied?
What are Current Research Trends in Genetic Mutations?
What Are the Treatment Options for Sickle Cell Disease?
What is Immunotherapy?
What is the Future of Genetic Research?
Follow Us
Top Searches
Autism Spectrum Disorder Congenital Heart Disease Cystic Fibrosis DNA Cloning Fragile X Syndrome Livestock Lynch Syndrome Neurodegenerative Diseases Sickle Cell Disease Thalassemia Patients

Partnered Content Networks

Relevant Topics