How Does Sanger Sequencing Compare to Next-Generation Sequencing (NGS)?
Next-Generation Sequencing (NGS) technologies have largely supplanted Sanger sequencing for many applications due to their higher throughput, speed, and cost-effectiveness. NGS can sequence millions of DNA fragments simultaneously, making it suitable for large-scale projects like whole-genome sequencing. However, Sanger sequencing remains the gold standard for validation and for applications requiring high accuracy and precision, such as clinical diagnostics and targeted gene analysis.
