L. C. J. Abel - Genetic Mutations

Author Information

Laurent Abel is a prominent researcher in the field of genetics, with a specific focus on the human genetics of infectious diseases. He is affiliated with the Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, located at Necker Hospital for Sick Children in Paris, France.

Research Contributions

Laurent Abel has made significant contributions to the understanding of genetic predispositions to infectious diseases. His recent research has delved into the genetic factors influencing the severity of viral diseases, including COVID-19. Notably, his 2022 publications cover topics such as the impact of a loss-of-function IFNAR1 allele in Polynesia, the protective effects of a common TMPRSS2 variant against severe COVID-19, and the role of type I IFN autoantibodies in COVID-19 mortality. His work also extends to identifying biomarkers for COVID-19 mortality and understanding genetic variants that disrupt intronic branchpoints. Earlier research includes studies on autosomal recessive STAT1 deficiency, common variable immunodeficiency linked to NFKB1 variants, and GATA2 deficiency.

Aliases

Laurent Abel is also known by several aliases in academic publications, including L Abel, L. Abel, L. C. J. Abel, and Laurent Abel.

Publication and Citation Metrics

Metric Value
Total Citations 44,577
h-index 114
Number of Papers 546

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