Detecting mutations in non-coding regions involves several techniques: - Next-Generation Sequencing (NGS): Allows for comprehensive analysis of the genome, including non-coding regions. - Chromatin Immunoprecipitation Sequencing (ChIP-Seq): Identifies DNA-protein interactions, useful for studying regulatory regions. - RNA-Seq: Provides insights into the functional consequences of non-coding mutations by analyzing changes in gene expression. - CRISPR/Cas9: This genome-editing tool can be used to introduce specific mutations in non-coding regions to study their effects.
