What are Some Examples of Medications Affected by Genetic Mutations?
Several medications are known to be affected by genetic mutations:
- Warfarin: Variants in the VKORC1 and CYP2C9 genes can influence the dosage requirements and risk of bleeding complications. - Clopidogrel: Mutations in the CYP2C19 gene can reduce the effectiveness of this antiplatelet drug, increasing the risk of cardiovascular events. - Statins: Variants in the SLCO1B1 gene can increase the risk of muscle toxicity.