What are the ethical considerations of using ZFNs?
As with any genome editing technology, the use of ZFNs raises ethical considerations, particularly when it comes to human genetic modification. There are concerns about the potential for unintended consequences, such as off-target effects that could lead to harmful mutations. Additionally, the use of ZFNs in germline cells, which can be passed on to future generations, raises questions about the long-term effects and the ethical implications of altering the human genome.
