polycyclic aromatic hydrocarbons (pahs)

Can the body repair PAH-induced DNA damage?


The body has several DNA repair mechanisms to correct PAH-induced DNA damage, such as nucleotide excision repair (NER) and base excision repair (BER). NER is particularly important for removing bulky DNA adducts caused by PAHs. However, the efficiency of these repair mechanisms can vary among individuals due to genetic variability. If DNA repair mechanisms are overwhelmed or impaired, the likelihood of mutations increases, leading to potential health risks.

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