The consequences of gene amplification can be varied and depend on the function of the gene being amplified. For example:
In cancer, amplification of oncogenes can lead to uncontrolled cell growth. In bacteria, amplification of antibiotic resistance genes can lead to increased resistance to antibiotics. In plants, gene amplification can lead to increased production of certain metabolites or resistance to environmental stresses.
Therefore, gene amplification can have both beneficial and detrimental effects depending on the context.